Week 8: Welcome to the World of Antibodies

This week’s lecture focused on antibodies and nanobodies. Before this class, I have had a special interest in antibodies and their potential for personalized therapeutics so I was looking forward to going through into this week. The assigned readings helped me to understand more about the naturally occurring antibodies and chemically synthesized binders, which basically function in a similar way.

I think that antibodies have a lot of therapeutic potential particularly because of their ability to be very readily modified to enhance the functions even further. I’m not too sure how big the difference in stability for antibodies and nanobodies are but from what I have read it’s quite a substantial difference. Nanobodies are also supposedly easier to produce, I suppose this would be true for chemically synthesized antibodies versus nanobodies.

Antibodies are the highest if not one of the highest kinds of drugs that is being approved right now so the market for antibodies is very high valued. Personally, Id like to explore if there’s more ways to modify the antibody to improve delivery to its specific target site.

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